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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Histoplasma capsulatum | Lectin-like component | Galactosylated surface molecules (mainly β-anomer) | Glycoconjugates | Murine macrophages | Binding | 19547878 | |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colonic epithelial cell lines (HT-29/HT-29-A7/HT-29-D4) | Gal(b1-1)Cer | Binding | 8464878 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Sputa of cystic fibrosis patients | Gal(b1-1)Cer | Binding | 8606110 |
| Escherichia coli | S-fimbriae (SfaA) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Brain endothelial cells | Gal(b1-1)Cer | Binding | 8098039 |
| Human immunodeficiency virus | HIV surface glycoprotein gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Neural cell lines | Gal(b1-1)Cer | Binding | 1857969 |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 15973004 |
| Human immunodeficiency virus | Envelope glycoprotein gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Neural receptor | Gal(b1-1)Cer | Binding | 1871126 |
| Escherichia coli | SfaA | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 15973004 | |
| Escherichia coli | S-fimbriae | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 15973004 | |
| Borrelia burgdorferi | "OspA, OspB, OspC" | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 16299269 | |
| Escherichia coli | F1C | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 15973004 | |
| Cytomegalovirus | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9780061 | |
| Borrelia burgdorferi | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 7622201 | |
| Borrelia burgdorferi | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 12628483 | |
| Borrelia hermsii | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 12628483 | |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gonorrhoeae patients | Gal(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Most tissues | Gal(b1-1)Cer | Not Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-1)Cer | Not Binding | 2470753 |
| Actinomyces naeslundii | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Most tissues | Gal(b1-1)Cer | Not Binding | 2358461 |
| Rotavirus | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 11160731 | |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 2468365 | |
| Propionibacterium freudenreichii | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium granulosum | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 2435422 | |
| Escherichia coli | F1C | Galactosylceramide (d18:1-h18:0-h24:0) | Monoglycosylceramides | Sigma | Gal(b1-1)Cer | Not Binding | 11877427 |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Galactosylceramide (hydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9712817 |
