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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Actinomyces naeslundii | Unknown | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat colon carcinoma | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat colon carcinoma | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | F1C | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat intestine | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Gonorrhoeae patients | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Human skin | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat colon carcinoma | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat small intestine | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Escherichia coli | PrsG (class III) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class I) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | Pyelonephritic adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Kidney | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Streptococcus pneumoniae | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Streptococcus suis | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7961660 |
| Escherichia coli | P-fimbriae | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | P-pili | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Epithelial cells in human urinary tract | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9007266 |
| Escherichia coli | PapG (class II) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes, Human uroepithelial cells | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7037645 |
| Escherichia coli | PapG (class II) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Epithelial cells in human urinary tract | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9007266 |
| Shigella dysenteriae | B subunit | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Actinomyces naeslundii | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Type-2 fimbrial lectins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Escherichia coli | (class II) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | P-fimbriae | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7721812 | |
| Escherichia coli | P-fimbriae | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Escherichia coli | P-pili | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11454740 | |
| Escherichia coli | P-pili | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 |
