Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Source Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Displaying entries 851 - 875 of 1840 in total
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source Glycan Sequence Binding ▲ PubMed ID
Foot-and-mouth disease virus VP1 (RGD peptide) Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) Glycosaminoglycans Extracellular matrix (ECM) Binding 9557639
Foot-and-mouth disease virus VP1 (RGD peptide) Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) Glycosaminoglycans Extracellular matrix (ECM) Binding 9557639
Foot-and-mouth disease virus VP1 (RGD peptide) Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) Glycosaminoglycans Extracellular matrix (ECM) Binding 9557639
Streptococcus pneumoniae CBPs (choline-binding proteins) Sialic acid Monosaccharides Cytokine-activated cells Binding 12640357
Helicobacter pylori SabA (sialic acid-binding adhesin) Sialic acid Monosaccharides Human neutrophils Binding 15689619
Rabies virus Unknown Sialic acid Monosaccharides Chicken embryo related cells Binding 3583664
Parvovirus Unknown Sialic acid (both O- and N-linked) Monosaccharides Nucleated bovine cells Binding 15269359
Escherichia coli SfaI-S Sialic acid Monosaccharides Epithelial cells, Extracellular matrix (ECM) Binding 10732678
Streptococcus gordonii Adhesins Sialic acid Monosaccharides HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) Binding 11035744
Streptococcus gordonii Hsa Sialic acid Monosaccharides Human oral cavity (erythrocytes and polymorphonuclear leukocytes) Binding 16177339
Streptococcus pneumoniae CbpA; SpsA; PbcA; PspC (CBPs) Sialic acid Monosaccharides Cytokine activated epithelial and endothelial cells Binding 10341176
Reovirus sigma 1 proteins Sialic acid Monosaccharides Murine intestine, Murine spleen, Murine liver, Murine brain, Human cholangiocarcinoma cells Binding 12813018
Bordetella pertussis Iron-induced surface-exposed proteins Sialic acid Monosaccharides Respiratory epithelial cells (A549) Binding 17727651
Plasmodium falciparum Unknown Sialic acid Monosaccharides Glycophorins A/B on the erythrocyte membrane Binding 3308959
Rotavirus Unknown Sialic acid Monosaccharides MA-104 cells Binding 10659372
Rotavirus VP8 Sialic acid Monosaccharides Epithelial cells of small intestine Binding 16511112
Paramyxovirus Unknown 116 kDa glycoprotein (containing sialic acid residues with N-linked glycans) N-glycans Neurones of all brain regions Binding 11666031
Polyoma virus Capsid VP1 GD1a-GT1b analog Sialoglycosphingolipids (broad range) Binding 18809496
Bordetella pertussis PT (subunit S3 of B oligomer) Gangliosides Sialoglycosphingolipids Human alveolar macrophages Binding 1729677
Helicobacter pylori Adhesins Gangliosides Sialoglycosphingolipids Human leukocytes, Human neutrophils Binding 10569742
Bordetella pertussis Pertussis toxin Gangliosides Sialoglycosphingolipids Human alveolar macrophages Binding 1729677
Influenza virus Unknown Gangliosides Sialoglycosphingolipids Bovine brain Binding 1740131
Clostridium botulinum Botulinum neurotoxin GT1b (complex with synaptotagmin II) Trisialoglycosphingolipids Presynaptic membrane of neuromuscular junction Binding 7527117
Clostridium botulinum BoNT/B GT1b (complex with synaptotagmin II) Trisialoglycosphingolipids Presynaptic membrane of neuromuscular junction Binding 7527117
Rotavirus Virus Spike Protein VP4 (mapped between aminoacids 93 and 208 of its trypsin cleavage fragment VP8) Sialic acid-containing cell compounds Glycoconjugates Binding 9261399

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