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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▼ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | F17 | N-Acetylglucosamine | Monosaccharides | Urine (microvilli of the intestinal epithelium of ruminants) | GlcNAc | Binding | 16564136 |
| Cryptococcus neoformans | Adhesins | N-Acetylglucosamine | Monosaccharides | Human lung epithelial cell line (A549) | GlcNAc | Binding | 9453390 |
| Cryptococcus neoformans | Adhesins | N-Acetylgalactosamine | Monosaccharides | Human lung epithelial cell line (A549) | GalNAc | Binding | 9453390 |
| Streptococcus pneumoniae | Adhesins | N-Acetylgalactosamine | Monosaccharides | Type-II lung cells, Vascular endothelial cells | GalNAc | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | D-Mannose | Monosaccharides | Type-II lung cells, Vascular endothelial cells | Man | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | D-Galactose | Monosaccharides | Vascular endothelial cells (only) | Gal | Binding | 7752878 |
| Escherichia coli | Type 1-pili | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | N-Acetylgalactosamine | Monosaccharides | Intestinal epithelial cells (T84) | GalNAc | Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Galactose | Monosaccharides | Intestinal epithelial cells (T84) | Gal | Binding | 17156748 |
| Clostridium botulinum | HA | N-Acetylgalactosamine | Monosaccharides | Intestinal epithelial cells (T84) | GalNAc | Binding | 17156748 |
| Clostridium botulinum | HA | Galactose | Monosaccharides | Intestinal epithelial cells (T84) | Gal | Binding | 17156748 |
| Rabies virus | Unknown | N-Acetylglucosamine | Monosaccharides | Chicken embryo related cells | GlcNAc | Binding | 3583664 |
| Rabies virus | Unknown | Galactose | Monosaccharides | Chicken embryo related cells | Gal | Binding | 3583664 |
| Rabies virus | Unknown | Mannose | Monosaccharides | Chicken embryo related cells | Man | Binding | 3583664 |
| Escherichia coli | FimCH-chaperone-adhesin complex | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
| Klebsiella pneumoniae | Unknown | Mannose | Monosaccharides | Respiratory tract | Man | Binding | 16564136 |
| Entamoeba histolytica | Raft-like plasma membrane domains | N-Acetylgalactosamine | Monosaccharides | Intestinal cells | GalNAc | Binding | 15322032 |
| Entamoeba histolytica | Raft-like plasma membrane domains | Galactose | Monosaccharides | Intestinal cells | Gal | Binding | 15322032 |
| Pseudomonas aeruginosa | Unknown | Fucose | Monosaccharides | Respiratory tract | Fuc | Binding | 16564136 |
| Pasteurella haemolytica | 68-kDa proteins | N-Acetylglucosamine | Monosaccharides | Bronchial lavages of sheep with pneumonic pasteurelosis | GlcNAc | Binding | 10570221 |
| Salmonella typhimurium | Unknown | Mannose | Monosaccharides | Intestinal cells | Man | Binding | 16564136 |
| Vibrio cholerae | MSHA (mannose/glucose-specific hemagglutinin) | Mannose | Monosaccharides | Patient with acute watery diarrhea | Man | Binding | 10219594 |
| Vibrio cholerae | MSHA (mannose/glucose-specific hemagglutinin) | Glucose | Monosaccharides | Patient with acute watery diarrhea | Glc | Binding | 10219594 |
| Escherichia coli | PrsG (class III) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PrsG (class III) G adhesins | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Acute cystitis patients | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding |
