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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Haemophilus influenzae | HifE (Pili family) | GM1(NeuAc/NeuGc) | Monosialoglycosphingolipids | Binding | 12640357 | ||
| Escherichia coli | PrsG (class III) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class I) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | P-fimbriae | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Influenza virus | Unknown | Sialyl-6-Paragloboside (S-6-PG; α2,6-sialylparagloboside) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GM3(NeuAc) | Monosialoglycosphingolipids | Human brain | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GM3(NeuGc) | Monosialoglycosphingolipids | Piglet intestine | NeuGc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | PapG (class II) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Legionella pneumophila | Adhesins | GM3(NeuAc) | Monosialoglycosphingolipids | Human epithelial cells (respiratory tract) | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 14687561 |
| Escherichia coli | F1C | GM3(NeuAc) | Monosialoglycosphingolipids | Human brain | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Actinomyces viscosus | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Human erythrocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | GM3(NeuGc) | Monosialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | NeuGc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Lactobacillus johnsonii | Unknown | GM3(NeuGc) | Monosialoglycosphingolipids | Horse erythrocytes | NeuGc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | GM3(NeuAc) | Monosialoglycosphingolipids | Human granulocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Lactobacillus casei | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Intestinal tract | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 8912650 |
| Actinomyces naeslundii | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Human erythrocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialyl-dimeric Lewis x (SdiLex) (GSL) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Escherichia coli | PsaA/B (pH-6 antigen) | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
| Escherichia coli | K99 | GM2(NeuGc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7849044 | |
| Escherichia coli | K99 | Sialylparagloboside(NeuGc) | Monosialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7849044 | |
| Vibrio cholerae | Cholera toxin | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Clostridium tetani | Tetanus toxin | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Influenza virus | Unknown | GM3(NeuGc) | Monosialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 |
