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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus pneumoniae | Adhesins | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 6886624 | |
| Pseudomonas aeruginosa | Pili | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 8574698 | |
| Haemophilus influenzae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Klebsiella pneumoniae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Streptococcus pneumoniae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Staphylococcus aureus | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Escherichia coli | F1C | unnamed ligand | Saccharides | Urine | GalNAc(b1-4)Gal(b | Binding | 16564136 |
| Escherichia coli | F1C | β-GalNac-1,4-β-Gal-containing structures | Saccharides | GalNAc(b1-4)Gal(b | Binding | 11401961 | |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
| Streptococcus pneumoniae | Adhesins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Burkholderia pseudomallei | Adhesins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Pharyngeal epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10497993 |
| Moraxella catarrhalis | Fimbriae | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Other than pharyngeal epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
| Candida albicans | 66-kDa subunit | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Pseudomonas aeruginosa | Type 4-pili | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Neisseria gonorrhoeae | 36-kDa proteins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9499377 |
| Legionella pneumophila | Adhesins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human epithelial cells (respiratory tract) | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 14687561 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Gonorrhoeae patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Pseudomonas aeruginosa | exoenzyme S | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human skin | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Actinomyces viscosus | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human brain | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Pseudomonas aeruginosa | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Cystic fibrosis patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 |
| Pseudomonas aeruginosa | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Lung | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Pseudomonas aeruginosa | Flagellin | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
