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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gonorrhoeae patients | Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Escherichia coli | PapG (class II) | Gb2 (Galabiosylceramide) | Diosylceramides | Epithelial cells in human urinary tract | Gal(a1-4)Gal(b1-1)Cer | Binding | 9007266 |
| Actinomyces viscosus | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Lactobacillus johnsonii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Histoplasma capsulatum | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Propionibacterium freudenreichii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human erythrocytes, Whole dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
| Cryptococcus neoformans | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Shigella dysenteriae | B subunit | Gb2 (Galabiosylceramide) | Diosylceramides | Human meconium | Gal(a1-4)Gal(b1-1)Cer | Binding | 3543013 |
| Lactobacillus casei | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Intestinal tract | Gal(b1-4)Glc(b1-1)Cer | Binding | 8912650 |
| Actinomyces naeslundii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Clostridium difficile | Toxin A | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Norovirus | Unknown | Blood group H1 antigen (HSA) | Glycoproteins | Human serum albumin | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Norovirus | Unknown | Lewis b (Leb-HSA) | Glycoproteins | Human serum albumin | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Clostridium difficile | Unknown | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Equine rhinitis A virus | Viral protein | α-mannose and α-glucose side chains of ConA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | Man/Glc | Binding | 15302947 |
| Pseudomonas aeruginosa | PA-IIL | Lewis a (Lea) (GSL) | Glycosphingolipids | Airways | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Escherichia coli | PapG (class II) G adhesins | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Patient with septic infection or pyelonephritis | Gal(a1-4)Gal | Binding | |
| Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Patient with septic infection or pyelonephritis | Gal(a1-4)Gal | Binding | |
| Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | |
| Escherichia coli | P-pili | Globo-series GSL | Glycosphingolipids | Uroepithelial cells, Erythrocytes | Gal(a1-4)Gal | Binding | 9973330 |
| Escherichia coli | PapG | Globo-series GSL | Glycosphingolipids | Uroepithelial cells, Erythrocytes | Gal(a1-4)Gal | Binding | 9973330 |
| Escherichia coli | PapG (class I) G adhesins | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Lewis a (Lea) (GSL) | Glycosphingolipids | Human skin | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
