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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▼ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Clostridium tetani | Unknown | GT1b analog | Trisialoglycosphingolipids | Synapse | Binding | 18809496 | |
| Pseudomonas aeruginosa | Adhesins | MUC1 mucin | Glycoproteins | Surface of chinese hamster ovary (CHO) cells | Binding | 11133508 | |
| Helicobacter pylori | Unknown | unnamed ligand | Oligosaccharides | Stomach | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Sputa of cystic fibrosis patients | Gal(b1-1)Cer | Binding | 8606110 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Sputa of cystic fibrosis patients | Gal(a1-4)Gal(b1-1)Cer | Binding | 8606110 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
| Escherichia coli | F1C | Galactosylceramide (d18:1-h18:0-h24:0) | Monoglycosylceramides | Sigma | Gal(b1-1)Cer | Not Binding | 11877427 |
| Streptococcus pneumoniae | CTB-PsaA pentamers | GM1 | Monosialoglycosphingolipids | Serum, Saliva, Nasal/bronchial wash samples | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15358234 |
| Neisseria meningitidis | PorA | C4b-binding protein (C4bp) | Glycoproteins | Serum | Binding | 15879129 | |
| Escherichia coli | AC/I-fimbriae (S-fimbrial family) | unknown carbohydrate ligand | Saccharides | Septicemic avian epithelial cells | Binding | 10992500 | |
| Norovirus | Unknown | Blood group H antigen | Disaccharides | Saliva | Fuc(a1-2)Gal | Binding | 18701592 |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | Saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus parasanguinis | FimA (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus sanguis | SsaB (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus gordonii | SspA (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus mutans | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus mutans | Pac (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus sobrinus | Pag (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus gordonii | SspB (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus sobrinus | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Saliva | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18701592 |
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | Saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 18701592 |
