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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species ▲ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Herpes simplex virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | Dextran sulfate | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human cervical cells | Binding | 9420059 | |
| Herpes virus | gH/gL | GAGs (glycosaminoglycans) | Glycosaminoglycans | Binding | 18301747 | ||
| Herpes virus | gp70 | GAGs (glycosaminoglycans) | Glycosaminoglycans | Binding | 18301747 | ||
| Histoplasma capsulatum | Lectin-like component | Galactosylated surface molecules (mainly β-anomer) | Glycoconjugates | Murine macrophages | Binding | 19547878 | |
| Histoplasma capsulatum | Adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Phagocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 19547878 |
| Histoplasma capsulatum | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Histoplasma capsulatum | Lectin-like component | unknown carbohydrate ligand | Saccharides | Human erythrocytes | Binding | 19547878 | |
| Human immunodeficiency virus | gp120 | Sulfatide (CSE) | Sulfoglycosphingolipids | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 |
| Human immunodeficiency virus | Envelope glycoprotein gp120 | Galactosyl sulfatide | Sulfoglycosphingolipids | Neural receptor | HSO3(-3)Gal(b1-1)Cer | Binding | 1871126 |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colonic epithelial cell lines (HT-29/HT-29-A7/HT-29-D4) | Gal(b1-1)Cer | Binding | 8464878 |
| Human immunodeficiency virus | HIV surface glycoprotein gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Neural cell lines | Gal(b1-1)Cer | Binding | 1857969 |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 15973004 |
| Human immunodeficiency virus | Envelope glycoprotein gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Neural receptor | Gal(b1-1)Cer | Binding | 1871126 |
| Human immunodeficiency virus | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | Dextran sulfate | Polysaccharides | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | Galactosylceramide (or derivative) | Monoglycosylceramides | Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 1378511 |
| Human immunodeficiency virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | Cluster of differentiation 4 (CD4) | Glycoproteins | Binding | 15973004 | ||
| Influenza virus | Hemagglutinin (HA) | GD1a | Disialoglycosphingolipids | Various human tissues (leukocytes/erythrocytes/small intestine/stomach/meconium/colon/pancreas) | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11030743 |
| Influenza virus | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Influenza virus | Unknown | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Influenza virus | Hemagglutinin (HA) | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Various human tissues (leukocytes/erythrocytes/small intestine/stomach/meconium/colon/pancreas) | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11030743 |
