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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | K1 | unnamed ligand | Disaccharides | Endothelial cells | GlcNAc(b1-4)GlcNAc | Binding | 16564136 |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Sulfatide (CSE) | Sulfoglycosphingolipids | Cell surface | HSO3(-3)Gal(b1-1)Cer | Binding | 10341176 |
| Mycoplasma pneumoniae | Adhesins | Sulfatide (CSE) | Sulfoglycosphingolipids | Erythrocytes | HSO3(-3)Gal(b1-1)Cer | Binding | 2470754 |
| Helicobacter pylori | Adhesins | Sulfatide (CSE) | Sulfoglycosphingolipids | Human gastric mucosa | HSO3(-3)Gal(b1-1)Cer | Binding | 2037054 |
| Human immunodeficiency virus | gp120 | Sulfatide (CSE) | Sulfoglycosphingolipids | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sulfatide (CSE) | Sulfoglycosphingolipids | Human meconium | HSO3(-3)Gal(b1-1)Cer | Binding | 9228091 |
| Human immunodeficiency virus | Envelope glycoprotein gp120 | Galactosyl sulfatide | Sulfoglycosphingolipids | Neural receptor | HSO3(-3)Gal(b1-1)Cer | Binding | 1871126 |
| Lactobacillus casei | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | Intestinal tract | HSO3(-3)Gal(b1-1)Cer | Binding | 8912650 |
| Escherichia coli | SfaA | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 | |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | S-fimbriae | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 | |
| Helicobacter pylori | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 16088272 | |
| Cytomegalovirus | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 9780061 | |
| Bordetella pertussis | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 | |
| Plasmodium falciparum | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 8574698 | |
| Actinobacillus pleuropneumoniae | LPS | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 10496867 | |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Sulfatide (CSE) | Sulfoglycosphingolipids | Piglet intestine | HSO3(-3)Gal(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | F1C | Sulfatide (CSE) | Sulfoglycosphingolipids | Porcine intestine | HSO3(-3)Gal(b1-1)Cer | Not Binding | 11877427 |
| Lactobacillus johnsonii | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | Human meconium | HSO3(-3)Gal(b1-1)Cer | Not Binding | 11087711 |
| Escherichia coli | F1C | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Not Binding | 10816509 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sulfo-gangliotetraosylceramide (Sulfo-GgO4) | Sulfoglycosphingolipids | Mouse intestine | HSO3(-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Sulfo-gangliotetraosylceramide (Sulfo-GgO4) | Sulfoglycosphingolipids | Mouse small intestine | HSO3(-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Lactobacillus johnsonii | Unknown | Sulfo-gangliotetraosylceramide (Sulfo-GgO4) | Sulfoglycosphingolipids | Mouse small intestine | HSO3(-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Cytomegalovirus | Unknown | SB1a (gangliotetraosylceramide bis-sulfate; SD1a) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-3)GalNAc(b1-4)[HSO3(-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9780061 | |
| Mycoplasma pneumoniae | Unknown | Sulfo-lactosylceramide (SM3) | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | HSO3(-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
