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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Entamoeba histolytica | Gal/GalNAc Lectins (260-kDa) | Galactose | Monosaccharides | c-Met on hepatocytes | Gal | Binding | 9878032 |
| Actinomyces naeslundii | Adhesins | Galactose | Monosaccharides | HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) | Gal | Binding | 11035744 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Galactose | Monosaccharides | Intestinal epithelial cells (T84) | Gal | Binding | 17156748 |
| Clostridium botulinum | HA | Galactose | Monosaccharides | Intestinal epithelial cells (T84) | Gal | Binding | 17156748 |
| Rabies virus | Unknown | Galactose | Monosaccharides | Chicken embryo related cells | Gal | Binding | 3583664 |
| Entamoeba histolytica | Raft-like plasma membrane domains | Galactose | Monosaccharides | Intestinal cells | Gal | Binding | 15322032 |
| Pseudomonas aeruginosa | PA-I | Galactose | Monosaccharides | Gal | Binding | 8574698 | |
| Entamoeba histolytica | Membrane-associated lectins (heavy(170-kDa)/light(35-or31-kDa) subunits) | Galactose | Monosaccharides | Gal | Binding | 10225860 | |
| Pseudomonas aeruginosa | PA-IL | Galactose | Monosaccharides | Gal | Binding | 10967261 | |
| Escherichia coli | Unknown | Galactose | Monosaccharides | Gal | Binding | 2885220 | |
| Entamoeba histolytica | 52-kDa recombinant fusion proteins | Galactose | Monosaccharides | Gal | Binding | 8574698 | |
| Haemophilus influenzae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Klebsiella pneumoniae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Streptococcus pneumoniae | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Staphylococcus aureus | Unknown | GalNAcβ4Gal-containing GSLs | Glycosphingolipids | GalNAc(b1-4)Gal | Binding | 15973004 | |
| Shigella dysenteriae | B subunit | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Human type B erythrocytes | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 3519828 |
| Shigella dysenteriae | B subunit | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Escherichia coli | Unknown | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | Gal-nLc4Cer; P1 antigen (GSL) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | B subunit | Gal-Gb3 | Oligoglycosylceramides | Rat small intestine | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | Gal-Gb3 | Oligoglycosylceramides | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Escherichia coli | Unknown | Gal-Gb3 | Oligoglycosylceramides | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | Gal-Gb3 | Oligoglycosylceramides | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Escherichia coli | PapG | Gal(a1-4)Gal in globo-series of glycolipids | Glycosphingolipids | Gal(a1-4)Gal | Binding | 10341176 |
