PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
---|---|---|---|---|---|---|---|
Lymphocytic choriomeningitis virus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes | Binding | 17360738 | |
Borrelia burgdorferi | DbpA | Decorin | Proteoglycans | Extracellular matrix (ECM) | Binding | 12761224 | |
Histoplasma capsulatum | Lectin-like component | unknown carbohydrate ligand | Saccharides | Human erythrocytes | Binding | 19547878 | |
Haemophilus influenzae | HMW1 | unknown carbohydrate ligand | Saccharides | Human epithelial cells (respiratory tract) | Binding | 10341176 | |
Haemophilus influenzae | HMW2 | unknown carbohydrate ligand | Saccharides | Human epithelial cells (respiratory tract) | Binding | 10341176 | |
Streptococcus gordonii | SspA/SspB (AgI/II family) | unknown carbohydrate ligand | Saccharides | Platelet | Binding | 16177339 | |
Escherichia coli | AC/I-fimbriae (S-fimbrial family) | unknown carbohydrate ligand | Saccharides | Septicemic avian epithelial cells | Binding | 10992500 | |
Streptococcus pneumoniae | PsaA (Lary family) | unknown carbohydrate ligand | Saccharides | Nasopharynx, Alveolar epithelial cells | Binding | 10341176 | |
Streptococcus gordonii | Hsa | unknown carbohydrate ligand | Saccharides | Platelet | Binding | 16177339 | |
Haemophilus influenzae | Hia | unknown carbohydrate ligand | Saccharides | Human conjunctival cells (respiratory tract) | Binding | 10341176 | |
Actinomyces odontolyticus | Unknown | unknown carbohydrate ligand | Saccharides | Tongue | Binding | 9712794 | |
Streptococcus pneumoniae | PclA (pneumococcal collagen-like protein A) | unknown carbohydrate ligand | Saccharides | Detroit 562/A549 cell lines | Binding | 18557785 | |
Bordetella pertussis | Pertactin | unknown carbohydrate ligand | Saccharides | Eukaryotic cells | Binding | 11348687 | |
Adeno-associated virus | Unknown | Glycoprotein with α2,6 N-linked sialic acid | Glycoproteins | NeuAc(a2-6)Gal(b1-4)GlcNAc | Binding | 16940521 | |
Escherichia coli | Unknown | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
Rotavirus | Unknown | Sialyl Lewis a (SLea) (GSL) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialyl-dimeric Lewis x (SdiLex) (GSL) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Parvovirus | Unknown | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 27671656 | |
Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4]Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc | Binding | 27671656 | |
Influenza virus | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
Helicobacter pylori | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9169796 | |
Influenza virus | Hemagglutinin (HA) | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
Cytomegalovirus | Unknown | SGLPG (Sulfated glucuronyl lactosaminyl paragloboside) | Sulfoglycosphingolipids | HSO3(-3)GlcA(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 | |
Rotavirus | VP8 (galectin) | Sialic acid(2-O-methyl-α-Neu5Ac (Neu5Ac2Me)) | Monosaccharides | Binding | 17306299 |
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Last updated: August 19, 2024