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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Polyoma virus | Capsid protein VP1 | Sialylated oligosaccharides | Oligosaccharides | Cell surface | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 8805524 |
| Polyoma virus | Unknown | Sialylated oligosaccharides | Oligosaccharides | Erythrocytes | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 6316632 |
| Influenza virus | Residues 226 (glutamine) and 228 (glycine) | Sialic acid linked to α2,3Galβ1,3GalNAc | Oligosaccharides | Avian/equine isolates | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 7975212 |
| Streptococcus sanguis | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Mycoplasma pneumoniae | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Mycoplasma gallisepticum | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Escherichia coli | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Streptococcus mitis | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Escherichia coli | PrsG (class III) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class I) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | P-fimbriae | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class II) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | Unknown | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Parvovirus | Unknown | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Shigella dysenteriae | Shiga toxin | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Shigella dysenteriae | Unknown | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Influenza virus | Unknown | GM1b | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | GM1b | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Hemagglutinin (HA) | GD1a | Disialoglycosphingolipids | Various human tissues (leukocytes/erythrocytes/small intestine/stomach/meconium/colon/pancreas) | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11030743 |
| Actinomyces naeslundii | Type-2 fimbrial lectins | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-IIb)) | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Clostridium botulinum | Neurotoxin (type B) | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9712688 | |
| Influenza virus | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Rotavirus | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 |
