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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | NeuGc3-nLc6Cer | Sialoglycosphingolipids | Rabbit thymus | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Rotavirus | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Mycoplasma pneumoniae | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Influenza virus | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Rat small intestine | [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Rat small intestine | [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | unnamed ligand | Oligoglycosylceramides | Rat small intestine | [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5 | Not Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | unnamed ligand | Oligoglycosylceramides | [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5 | Not Binding | 2435422 | |
| Escherichia coli | Unknown | unnamed ligand | Oligoglycosylceramides | [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5 | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | unnamed ligand | Oligoglycosylceramides | [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5 | Not Binding | 2435422 | |
| Parvovirus | Unknown | O-linked alpha 2,3 neuraminic acid on glycophorin A (GPA) | Glycoproteins | Human erythrocytes | Binding | 15750863 | |
| Streptococcus gordonii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins in the presence of sialic acid | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 | |
| Rubulavirus | Unknown | N-linked sialylated glycoproteins | Glycoproteins | Pig neurons, glial cells | Binding | 16459111 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Borrelia afzelii | Unknown | Dermatan sulfate | Glycosaminoglycans | Glial cells | Binding | 10085013 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparan sulfate | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparan sulfate | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparan sulfate | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparan sulfate | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Borrelia garinii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia garinii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia garinii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 |
