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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▲ |
|---|---|---|---|---|---|---|---|
| Haemophilus influenzae | HMW2 | Oligosaccharides rich in sialic acid | Oligosaccharides | Human epithelial cells | Binding | 12640357 | |
| Haemophilus influenzae | Hia | Oligosaccharides rich in sialic acid | Oligosaccharides | Human conjunctival cells (respiratory tract) | Binding | 12640357 | |
| Streptococcus pneumoniae | CBPs (choline-binding proteins) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine-activated cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12640357 |
| Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Eukaryotic cells | Man | Binding | 12640357 |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus parasanguinis | FimA (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus sanguis | SsaB (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus gordonii | SspA (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus mutans | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus mutans | Pac (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus sobrinus | Pag (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus gordonii | SspB (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus sobrinus | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Fucosylated Lewis b (Leb) histoblood group antigens | Oligosaccharides | Mucosal surface of the gastric epithelium | Binding | 12640357 | |
| Haemophilus influenzae | HifE (Pili family) | GM1(NeuAc/NeuGc) | Monosialoglycosphingolipids | Binding | 12640357 | ||
| Haemophilus influenzae | HifE (Pili family) | GM1(NeuAc/NeuGc) | Monosialoglycosphingolipids | Binding | 12640357 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Galactose on sulfated glycolipids | Glycolipids | Gal | Binding | 12640357 | |
| Escherichia coli | PrsG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Escherichia coli | PapG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Enterococcus faecalis | EfaA (Lary family) | L-Fucose-containing residues | Saccharides | Fuc | Binding | 12640357 | |
| Neisseria gonorrhoeae | N-methylphenyl-alanine pili | Glucosamine-galactose carbohydrate | Disaccharides | Binding | 12640357 | ||
| Streptococcus pneumoniae | PsaA (Lary family) | N-acetylhexosamine-galactose | Disaccharides | Binding | 12640357 | ||
| Bordetella pertussis | Pertactin | Integrins | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | CBPs (choline-binding proteins) | Sialic acid | Monosaccharides | Cytokine-activated cells | Binding | 12640357 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 |
