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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Pseudomonas aeruginosa | Type 4-pili | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Pseudomonas aeruginosa | Type 4-pili | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Epithelial cells | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Pseudomonas aeruginosa | exoenzyme S | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Pseudomonas aeruginosa | Flagellin | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Pseudomonas aeruginosa | LPS | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Escherichia coli | P-pili | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Epithelial cells in human urinary tract | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9007266 |
| Escherichia coli | PapG (class II) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Epithelial cells in human urinary tract | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9007266 |
| Escherichia coli | P-pili | Gb2 (Galabiosylceramide) | Diosylceramides | Epithelial cells in human urinary tract | Gal(a1-4)Gal(b1-1)Cer | Binding | 9007266 |
| Escherichia coli | PapG (class II) | Gb2 (Galabiosylceramide) | Diosylceramides | Epithelial cells in human urinary tract | Gal(a1-4)Gal(b1-1)Cer | Binding | 9007266 |
| Rotavirus | VP8 | Sialic acid | Monosaccharides | Epithelial cells of small intestine | Binding | 16511112 | |
| Escherichia coli | SfaI-S | Sialic acid | Monosaccharides | Epithelial cells, Extracellular matrix (ECM) | Binding | 10732678 | |
| Polyoma virus | Unknown | Sialylated oligosaccharides | Oligosaccharides | Erythrocytes | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 6316632 |
| Mycoplasma pneumoniae | Adhesins | Sulfatide (CSE) | Sulfoglycosphingolipids | Erythrocytes | HSO3(-3)Gal(b1-1)Cer | Binding | 2470754 |
| Streptococcus suis | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7961660 |
| Polyoma virus | Unknown | Sialylated oligosaccharides | Oligosaccharides | Erythrocytes | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc | Binding | 6316632 |
| Streptococcus suis | Adhesins | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7961660 |
| Mycoplasma pneumoniae | Adhesins | hCG (human chorionic gonadotropin) | Glycoproteins | Erythrocytes | Binding | 2470754 | |
| Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Eukaryotic cells | Man | Binding | 12640357 |
| Bordetella pertussis | Pertactin | unknown carbohydrate ligand | Saccharides | Eukaryotic cells | Binding | 11348687 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparan sulfate | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparan sulfate | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparan sulfate | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparan sulfate | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | αvβ3 Integrin (independent of expression of Heparan sulfate on cell-sulface) | Glycoproteins | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 |
