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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus sobrinus | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus parasanguinis | FimA (Lral family); localized to the tip of peritrichous surface fimbria | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Influenza virus | Unknown | Salivary glycoprotein | Glycoproteins | Human saliva | Binding | 1740131 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | Salivary glycoprotein (gp340) | Glycoproteins | Human oral cavity (in fluid and surface-associated phases) | Binding | 16177339 | |
| Helicobacter pylori | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Human stomach associated with gastritis and peptic ulcer disease | Binding | 11007786 | |
| Streptococcus agalactiae | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Neonatal meningitis | Binding | 11007786 | |
| Streptococcus gordonii | Hsa | Salivary glycoprotein (gp340) | Glycoproteins | Human oral cavity (surface-bound) | Binding | 16177339 | |
| Streptococcus mutans | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Dental plaque (caries-associated) | Binding | 11007786 | |
| Escherichia coli | S-fimbriae (SfaA) | Seminolipid (Sulfogalactosylglycerolipid) | Glycolipids | Brain endothelial cells | Gal(3SO4)(b1-1)-alkylacylglycerol | Binding | 8098039 |
| Mycoplasma pneumoniae | Unknown | Seminolipid (Sulfogalactosylglycerolipid) | Glycolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(3SO4)(b1-3)-alkylacylglycerol | Binding | 2470753 |
| Influenza virus | Unknown | Sia2-3Gal-containing receptors | Glycoconjugates | NeuAc(a2-3)Gal | Binding | 9882316 | |
| Streptococcus pneumoniae | CBPs (choline-binding proteins) | Sialic acid | Monosaccharides | Cytokine-activated cells | Binding | 12640357 | |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialic acid | Monosaccharides | Human neutrophils | Binding | 15689619 | |
| Rabies virus | Unknown | Sialic acid | Monosaccharides | Chicken embryo related cells | Binding | 3583664 | |
| Escherichia coli | SfaI-S | Sialic acid | Monosaccharides | Epithelial cells, Extracellular matrix (ECM) | Binding | 10732678 | |
| Streptococcus gordonii | Adhesins | Sialic acid | Monosaccharides | HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) | Binding | 11035744 | |
| Streptococcus gordonii | Hsa | Sialic acid | Monosaccharides | Human oral cavity (erythrocytes and polymorphonuclear leukocytes) | Binding | 16177339 | |
| Streptococcus pneumoniae | CbpA; SpsA; PbcA; PspC (CBPs) | Sialic acid | Monosaccharides | Cytokine activated epithelial and endothelial cells | Binding | 10341176 | |
| Reovirus | sigma 1 proteins | Sialic acid | Monosaccharides | Murine intestine, Murine spleen, Murine liver, Murine brain, Human cholangiocarcinoma cells | Binding | 12813018 | |
| Bordetella pertussis | Iron-induced surface-exposed proteins | Sialic acid | Monosaccharides | Respiratory epithelial cells (A549) | Binding | 17727651 | |
| Plasmodium falciparum | Unknown | Sialic acid | Monosaccharides | Glycophorins A/B on the erythrocyte membrane | Binding | 3308959 | |
| Rotavirus | Unknown | Sialic acid | Monosaccharides | MA-104 cells | Binding | 10659372 | |
| Rotavirus | VP8 | Sialic acid | Monosaccharides | Epithelial cells of small intestine | Binding | 16511112 | |
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 8574698 | ||
| Newcastle disease virus | HN(hemagglutinin-neuraminidase) glycoproteins | Sialic acid | Monosaccharides | Binding | 17205603 |
