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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus gordonii | SspB (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus sobrinus | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus parasanguinis | FimA (Lral family); localized to the tip of peritrichous surface fimbria | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Influenza virus | Unknown | Salivary glycoprotein | Glycoproteins | Human saliva | Binding | 1740131 | |
| Bordetella pertussis | Iron-induced surface-exposed proteins | Mucin | Glycoproteins | Respiratory epithelial cells (A549) | Binding | 17727651 | |
| Campylobacter upsaliensis | Unknown | Mucin | Glycoproteins | Human small intestine | Binding | 8926069 | |
| Streptococcus mutans | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Dental plaque (caries-associated) | Binding | 11007786 | |
| Listeria innocua | Unknown | Mannose 6-phosphate insulin-like growth factor-II receptor (M6P/IGF-IIR) | Glycoproteins | Fetal calf serum | Binding | 16369013 | |
| Rhinovirus | Unknown | ICAM-1 (intercellular adhesion molecule-1) domain1/2 | Glycoproteins | Primary chicken embryo fibroblasts (CEFs) | Binding | 1356290 | |
| Listeria monocytogenes | Unknown | Mannose 6-phosphate insulin-like growth factor-II receptor (M6P/IGF-IIR) | Glycoproteins | Fetal calf serum | Binding | 16369013 | |
| Neisseria meningitidis | PorA | C4b-binding protein (C4bp) | Glycoproteins | Serum | Binding | 15879129 | |
| Pseudomonas aeruginosa | Flagellin | MUC1 mucin | Glycoproteins | Epithelial cells | Binding | 11880301 | |
| Bordetella pertussis | Unknown | Fetuin | Glycoproteins | Bovine | Binding | 14532091 | |
| Bordetella pertussis | Fim2 (H1/H2) | Heparin | Glycosaminoglycans | ECM | Binding | 11348687 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Bordetella pertussis | FHA (442-863) | Heparin | Glycosaminoglycans | WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM) | Binding | 11348687 | |
| Bordetella pertussis | FHA (442-863) | Heparin | Glycosaminoglycans | Respiratory epithelial cells | Binding | 17106803 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Herpes simplex virus | Unknown | Heparin | Glycosaminoglycans | Human cervical cells | Binding | 9420059 | |
| Borrelia burgdorferi | BBK32 | Heparin | Glycosaminoglycans | Mammalian cell surface | Binding | 16368999 | |
| Shigella dysenteriae | Stx | Platelet-specific GSL (Stx band 0.03) | Glycosphingolipids | Human platelets | Binding | 9712788 | |
| Cryptococcus neoformans | Adhesins | Sucrose | Monosaccharides | Human lung epithelial cell line (A549) | Binding | 9453390 | |
| Cryptococcus neoformans | Adhesins | Inositol | Non-glycosylated Lipids | Human lung epithelial cell line (A549) | Binding | 9453390 | |
| Clostridium botulinum | Botulinum neurotoxin (type D) | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | Presynaptic neuronal cells | Binding | 18242046 | |
| Pseudomonas aeruginosa | exoenzyme S | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | Epithelial cells | Binding | 9224879 |
