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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | FimCH-chaperone-adhesin complex | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
| Pseudomonas aeruginosa | PA-IIL | D-Mannose | Monosaccharides | Man | Binding | 10967261 | |
| Pseudomonas aeruginosa | PA-IIL (47-kDa) | D-Mannose | Monosaccharides | Man | Binding | 15049333 | |
| Enterococcus faecalis | EfaA (Lary family) | D-Galactose-containing residues | Saccharides | Gal | Binding | 12640357 | |
| Streptococcus pneumoniae | Adhesins | D-Galactose | Monosaccharides | Vascular endothelial cells (only) | Gal | Binding | 7752878 |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | D-Galactose | Monosaccharides | Gal | Binding | 15049333 | |
| Clostridium botulinum | Neurotoxin (type B) | Complex of synaptotagmin II and ganglioside GT1b or GD1a | Glycoconjugates | Binding | 9712688 | ||
| Clostridium botulinum | Unknown | Complex of synaptotagmin II and ganglioside GT1b or GD1a | Glycoconjugates | Binding | 9712688 | ||
| Bordetella pertussis | FHA (tail region) | Complement receptor 3 (CR3) integrins | Glycoproteins | Macrophages | Binding | 11348687 | |
| Shigella dysenteriae | Adhesins | Colonic mucin | Glycoproteins | Colon | Binding | 11381327 | |
| Klebsiella pneumoniae | MrkD-pili | Collagen (type V) | Glycoproteins | Binding | 10341176 | ||
| Klebsiella pneumoniae | MrkD-pili | Collagen (type V) | Glycoproteins | Binding | 12640357 | ||
| Streptococcus gordonii | SspA/SspB (AgI/II family) | Collagen (type I) | Glycoproteins | humHn oral cavity (root dentine) | Binding | 16177339 | |
| Borrelia burgdorferi | "DbpA, DbpB, Bgp" | Collagen (type I) | Glycoproteins | Binding | 16299269 | ||
| Escherichia coli | FimH | Collagen | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Collagen | Glycoproteins | Binding | 12010488 | ||
| Human immunodeficiency virus | Unknown | Cluster of differentiation 4 (CD4) | Glycoproteins | Binding | 15973004 | ||
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Chondroitin sulfate C | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Chondroitin sulfate A | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Borrelia burgdorferi | Unknown | Chondroitin 6-sulfate (C-6S) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Borrelia burgdorferi | Unknown | Chondroitin 4-sulfate (C-4S) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Escherichia coli | F1C | Ceramide | Non-glycosylated Lipids | Cer | Not Binding | 10816509 | |
| Escherichia coli | Verotoxin (1; B-subunit) | CD77 (Globotriaosylceramide; Gb3) | Oligoglycosylceramides | Germinal center B lymphocytes, Burkitt's lymphoma cells | Gal(a1-4)Gal | Binding | 7516406 |
| Escherichia coli | Unknown | CD77 (Globotriaosylceramide; Gb3) | Oligoglycosylceramides | Germinal center B lymphocytes, Burkitt's lymphoma cells | Gal(a1-4)Gal | Binding | 7516406 |
| Escherichia coli | FimH | CD48 | Glycoproteins | Binding | 12010488 |
