PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
---|---|---|---|---|---|---|---|
Helicobacter pylori | Unknown | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9169796 | |
Rotavirus | Unknown | Lactosylceramide (d18:1-16:0/24:1) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
Escherichia coli | F1C | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 10816509 | |
Propionibacterium granulosum | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2468365 | |
Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Not Binding | 18701592 | |
Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Not Binding | 18701592 | |
Helicobacter mustelae | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
Helicobacter bilis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
Helicobacter pylori | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
Escherichia coli | K88ab/K88ac/K88ad | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
Helicobacter felis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
Shigella dysenteriae | Shiga toxin | unnamed ligand | Glycosphingolipids | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
Norovirus | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 18701592 | |
Helicobacter canis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
Shigella dysenteriae | Unknown | unnamed ligand | Glycosphingolipids | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
Propionibacterium freudenreichii | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
Escherichia coli | PsaA/B (pH-6 antigen) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9712817 | |
Rotavirus | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 11160731 | |
Rotavirus | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 11160731 | |
Yersinia pestis | PsaA/B (pH-6 antigen) | Galactosylceramide (nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 9712817 | |
Yersinia pestis | PsaA/B (pH-6 antigen) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9712817 | |
Propionibacterium granulosum | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 2468365 | |
Propionibacterium granulosum | Lectin-like proteins (adhesin) | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 2468365 | |
Cytomegalovirus | Unknown | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Not Binding | 9780061 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
GlyCosmos Portal v4.0.0
Last updated: August 19, 2024