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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 18599458 | |
| Escherichia coli | hLT | Blood group A antigen analog | Oligosaccharides | Binding | 18809496 | ||
| Plasmodium falciparum | Unknown | N-linked oligosaccharides of glycophorins | Oligosaccharides | Binding | 8574698 | ||
| Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc | Not Binding | 27671656 | |
| Mumps virus | MuV-HN | Glycans containing α2,6-linked sialic acid | Oligosaccharides | NeuAc(a2-6)Gal(b1-4)GlcNAc | Not Binding | 27671656 | |
| Mumps virus | MuV-HN | Glycans containing α2,6-linked sialic acid | Oligosaccharides | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc | Not Binding | 27671656 | |
| Mumps virus | MuV-HN | Glycans containing α2,6-linked sialic acid | Oligosaccharides | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc | Not Binding | 27671656 | |
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | Saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Not Binding | 18701592 |
| Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Human saliva | Gal(a1-3)[Fuc(a1-2)]Gal | Not Binding | 16707048 |
| Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Saliva | Gal(a1-3)[Fuc(a1-2)]Gal | Not Binding | 18701592 |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
| Helicobacter felis | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
| Helicobacter canis | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Not Binding | 12704182 | ||
| Actinomyces naeslundii | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Escherichia coli | Unknown | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Binding | 2435422 | |
| Actinomyces viscosus | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 2435422 | |
| Shigella dysenteriae | Unknown | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 2435422 | |
| Neisseria meningitidis | OpcA | Sialic acid-containing polysaccharides | Polysaccharides | Epithelial cells | Binding | 18076035 | |
| Bordetella pertussis | FHA (442-863) | Dextran sulfate | Polysaccharides | WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM) | Binding | 11348687 | |
| Human immunodeficiency virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human T cells | Binding | 9420059 |
