PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
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Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species ▼ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
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Bordetella pertussis | PT (subunit S2 of B oligomer) | Fetuin | Glycoproteins | Binding | 1729677 | ||
Bordetella pertussis | Pertactin | Integrins | Glycoproteins | Binding | 10341176 | ||
Bordetella pertussis | Pertactin | Integrins | Glycoproteins | Binding | 12640357 | ||
Bordetella pertussis | Iron-induced surface-exposed proteins | Sialic acid | Monosaccharides | Respiratory epithelial cells (A549) | Binding | 17727651 | |
Bordetella pertussis | PT (subunit S3 of B oligomer) | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 | |
Bordetella pertussis | Pertussis toxin | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 | |
Bordetella pertussis | CRD (carbohydrate recognition domain) of Fha (Filamentous Hemagglutinin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Respiratory ciliated cells, Alveolar macrophages | Gal(b1-4)Glc(b1-1)Cer | Binding | 8514379 |
Bordetella pertussis | Pertussis toxin | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
Bordetella pertussis | FHA (1141-1279) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Ciliated epithelium of the respiratory tract | Gal(b1-4)Glc(b1-1)Cer | Binding | 11348687 |
Bordetella pertussis | PT (subunit S2 of B oligomer) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
Bordetella pertussis | PT (subunits S2/S3 of B oligomer) | Glucosylceramide | Monoglycosylceramides | Human cilia of the respiratory epithelium | Glc(b1-1)Cer | Binding | 1729677 |
Bordetella pertussis | Pertussis toxin | Glucosylceramide | Monoglycosylceramides | Human cilia of the respiratory epithelium | Glc(b1-1)Cer | Binding | 1729677 |
Bordetella pertussis | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human lung, Human trachea | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 1918002 |
Bordetella pertussis | FimD | VLA-5 (very late activation antigen 5) | Glycoproteins | Monocytes | Binding | 11348687 | |
Bordetella pertussis | Pertactin | unknown carbohydrate ligand | Saccharides | Eukaryotic cells | Binding | 11348687 | |
Bordetella pertussis | Pertussis toxin | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
Bordetella pertussis | PT (subunit S2 of B oligomer) | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
Bordetella parapertussis | Adhesins | terminal Gal(3SO4) β1- residues | Sulfoglycosphingolipids | Gal(3SO4)(b | Binding | 1918002 | |
Bordetella parapertussis | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 1918002 | |
Anaplasma phagocytophilum | "P-selectin mimic, MSP2" | Fucosylated PSGL-1 (P-selectin glycoprotein ligand-1) | Glycoproteins | Binding | 16299269 | ||
Anaplasma marginale | "MSP1a, MSP1b, MSP2" | unknown carbohydrate ligand | Saccharides | Binding | 16299269 | ||
Adenovirus | Fibre proteins | HSA glycoconjugates | Glycoproteins | Human corneal epithelial(HEC) cells | Binding | 15678425 | |
Adeno-associated virus | Unknown | Glycoproteins with α2,3 N-linked sialic acid | Glycoproteins | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 16940521 | |
Adeno-associated virus | Unknown | Glycoprotein with α2,6 N-linked sialic acid | Glycoproteins | NeuAc(a2-6)Gal(b1-4)GlcNAc | Binding | 16940521 | |
Adeno-associated virus | Unknown | NeuAcα2-3GalNAcβ1-4GlcNAc | Oligosaccharides | NeuAc(a2-3)GalNAc(b1-4)GlcNAc | Binding | 16940521 |
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Last updated: August 19, 2024