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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Chondroitin sulfate A | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Chondroitin sulfate C | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Sporothrix schenckii | Yeast cells and conidia | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 11598061 | |
| Leptospira interrogans | Lsa24 | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 16954400 | |
| Sporothrix schenckii | Yeast cells and hyphae | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Sporothrix schenckii | Yeast cells and hyphae | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 9557639 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | De-N-sulfated heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Dextran sulfate | Polysaccharides | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Borrelia burgdorferi | DbpA | Decorin | Proteoglycans | Extracellular matrix (ECM) | Binding | 12761224 | |
| Equine rhinitis A virus | Viral protein | NeuAc/GlcNAc/(GlcNAc)n side chains of WGA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | NeuAc/GlcNAc/(GlcNAc)n | Binding | 15302947 |
| Equine rhinitis A virus | Viral protein | NeuAcα2,3-Gal/GalNAc side chains of MAA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | NeuAc(a2-3)Gal/GalNAc | Binding | 15302947 |
| Equine rhinitis A virus | Viral protein | α-mannose and α-glucose side chains of ConA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | Man/Glc | Binding | 15302947 |
| Listeria innocua | Unknown | Mannose 6-phosphate insulin-like growth factor-II receptor (M6P/IGF-IIR) | Glycoproteins | Fetal calf serum | Binding | 16369013 | |
| Listeria monocytogenes | Unknown | Mannose 6-phosphate insulin-like growth factor-II receptor (M6P/IGF-IIR) | Glycoproteins | Fetal calf serum | Binding | 16369013 | |
| Lassa virus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes | Binding | 17360738 | |
| Lymphocytic choriomeningitis virus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes | Binding | 17360738 | |
| Actinomyces viscosus | Unknown | unnamed ligand | Sialoglycosphingolipids | Frog brain | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Sialoglycosphingolipids | Frog brain | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | unnamed ligand | Sialoglycosphingolipids | Frog brain | Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
