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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▼ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Influenza virus | Hemagglutinin (HA) | Gangliosides | Glycosphingolipids | Human leukocytes | Binding | 11030743 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human erythrocytes, Human leukocytes, Human placenta | Binding | 9169796 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Rat small intestine, Wild boar intestine, Monkey intestine | Binding | 9169796 | |
| Pseudomonas aeruginosa | LecB | alpha-methyl-fucoside | Monosaccharides | A549 cells | Binding | 19237519 | |
| Pseudomonas aeruginosa | LecA | Alpha-methyl-galactoside | Monosaccharides | A549 cells | Binding | 19237519 | |
| Escherichia coli | K88ab | GlcNAc residues in the core of N-glycan on pSTf (porcine serum transferrin) | N-glycans | Porcine serum | Binding | 11953368 | |
| Shigella dysenteriae | Adhesins | Lipid extracts of Hep-2 cells | Non-glycosylated Lipids | HEp-2 cells | Binding | 11381327 | |
| Escherichia coli | P-pili | Surfactant-like particles (SLP) | Non-glycosylated Lipids | Human colonocytes and enterocytes | Binding | 10531281 | |
| Escherichia coli | PapD-PapG (class I) | Surfactant-like particles (SLP) | Non-glycosylated Lipids | Human colonocytes and enterocytes | Binding | 10531281 | |
| Lassa virus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes | Binding | 17360738 | |
| Lymphocytic choriomeningitis virus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes | Binding | 17360738 | |
| Borrelia burgdorferi | DbpA | Decorin | Proteoglycans | Extracellular matrix (ECM) | Binding | 12761224 | |
| Histoplasma capsulatum | Lectin-like component | unknown carbohydrate ligand | Saccharides | Human erythrocytes | Binding | 19547878 | |
| Haemophilus influenzae | HMW1 | unknown carbohydrate ligand | Saccharides | Human epithelial cells (respiratory tract) | Binding | 10341176 | |
| Haemophilus influenzae | HMW2 | unknown carbohydrate ligand | Saccharides | Human epithelial cells (respiratory tract) | Binding | 10341176 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | unknown carbohydrate ligand | Saccharides | Platelet | Binding | 16177339 | |
| Escherichia coli | AC/I-fimbriae (S-fimbrial family) | unknown carbohydrate ligand | Saccharides | Septicemic avian epithelial cells | Binding | 10992500 | |
| Streptococcus pneumoniae | PsaA (Lary family) | unknown carbohydrate ligand | Saccharides | Nasopharynx, Alveolar epithelial cells | Binding | 10341176 | |
| Streptococcus gordonii | Hsa | unknown carbohydrate ligand | Saccharides | Platelet | Binding | 16177339 | |
| Haemophilus influenzae | Hia | unknown carbohydrate ligand | Saccharides | Human conjunctival cells (respiratory tract) | Binding | 10341176 | |
| Actinomyces odontolyticus | Unknown | unknown carbohydrate ligand | Saccharides | Tongue | Binding | 9712794 | |
| Streptococcus pneumoniae | PclA (pneumococcal collagen-like protein A) | unknown carbohydrate ligand | Saccharides | Detroit 562/A549 cell lines | Binding | 18557785 | |
| Bordetella pertussis | Pertactin | unknown carbohydrate ligand | Saccharides | Eukaryotic cells | Binding | 11348687 | |
| Escherichia coli | SafS | α-sialyl-2-3-β-galactose | Disaccharides | Binding | 12640357 | ||
| Clostridium botulinum | Neurotoxin (type B) | Complex of synaptotagmin II and ganglioside GT1b or GD1a | Glycoconjugates | Binding | 9712688 |
