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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Actinomyces odontolyticus | Type 2-fimbriae | β-linked galactosamine | Saccharides | Tongue | GalNAc(b | Not Binding | 9712794 |
| Actinomyces odontolyticus | Type 2-fimbriae | β-linked galactosamine | Saccharides | Plaque | GalNAc(b 2:1 | Not Binding | 9712794 |
| Escherichia coli | NeuC protein of K1 capsule (UDP GlcNAc 2-epimerase)) | GlcNAc-6-P | Saccharides | Not Binding | 14729696 | ||
| Borrelia burgdorferi | DbpA | Decorin | Proteoglycans | Extracellular matrix (ECM) | Binding | 12761224 | |
| Borrelia burgdorferi | "DbpA, DbpB, Bgp" | Decorin | Proteoglycans | Binding | 16299269 | ||
| Influenza virus | Unknown | Endothelial cell-specific molecule (ESM) | Proteoglycans | Not Binding | 1740131 | ||
| Neisseria meningitidis | OpcA | Sialic acid-containing polysaccharides | Polysaccharides | Epithelial cells | Binding | 18076035 | |
| Bordetella pertussis | FHA (442-863) | Dextran sulfate | Polysaccharides | WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM) | Binding | 11348687 | |
| Human immunodeficiency virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | Dextran sulfate | Polysaccharides | Human T cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | Pentosan polysulfate (PP) | Polysaccharides | HeLa cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | Dextran sulfate | Polysaccharides | HeLa cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | Dextran sulfate | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human epithelial cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | Dextran sulfate | Polysaccharides | Human epithelial cells | Binding | 9420059 | |
| Plasmodium falciparum | Unknown | Polylactosamine of band 3 | Polysaccharides | Binding | 8574698 | ||
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Dextran sulfate | Polysaccharides | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Actinomyces naeslundii | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Escherichia coli | Unknown | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Binding | 2435422 | |
| Actinomyces viscosus | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 2435422 | |
| Shigella dysenteriae | Unknown | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 2435422 | |
| Escherichia coli | S-fimbriae | unnamed ligand | Oligosaccharides | Neural cell lines | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 16564136 |
