Adaptor protein complex binds to TL receptor at the plasma membrane

Summary
Organism
Drosophila melanogaster (fruit fly)
Reactome
R-DME-214863
PubChem
R-DME-214863
Description
  • Spatzle (SPZ) dimer binding leads to Toll (TL) receptor homodimerisation and activation.
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P08953 Protein toll
  • CG5490
  • Tl
view
P48607 Protein spaetzle
  • CG6134
  • spz
view
Q7K105 LD20892p
  • CG2078
  • DMMYD88
  • DmMyD88
  • DmMyd88
  • Dmel\CG2078
  • Dmel_CG2078
  • EP(2)2535
  • Kra
  • LD20892
  • MYD88
  • MyD88
  • Myd88
  • Myd88F
  • dMYd88
  • dMyD88
  • dMyd88
  • kra
  • myd88
view

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026