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Acyl chain remodelling of PG

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-1482925

PubChem

R-HSA-1482925

Description

In the acyl chain remodelling pathway (Lands cycle), phosphatidylglycerol (PG) is hydrolyzed by phopholipases and subsequently reacylated by acyltransferases. These cycles modify the fatty acid composition of glycerophospholipids to generate diverse molecules asymmetrically distributed in the cell membrane. The events occur additionally in the inner mitochondria membranes (IM) as well as in the endoplasmic reticulum (ER) membrane (Ghomashchi et al. 2010, Singer et al. 2002, Cao et al. 2008, Yang et al. 2004, Nie et al. 2010).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 10** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O15496	Group 10 secretory phospholipase A2	PLA2G10	view
P14555	Phospholipase A2, membrane associated	PLA2B PLA2G2A PLA2L RASF-A	view
P47712	Cytosolic phospholipase A2	CPLA2 PLA2G4 PLA2G4A	view
Q13018	Secretory phospholipase A2 receptor	CLEC13C PLA2R1	view
Q643R3	Lysophospholipid acyltransferase LPCAT4	AGPAT7 AYTL3 LPCAT4 LPEAT2	view
Q8NF37	Lysophosphatidylcholine acyltransferase 1	AYTL2 LPCAT1 PFAAP3	view
Q9BZM2	Group IIF secretory phospholipase A2	PLA2G2F	view
Q9NZ20	Group 3 secretory phospholipase A2	PLA2G3	view
Q9NZK7	Group IIE secretory phospholipase A2	PLA2G2E	view
Q9UNK4	Group IID secretory phospholipase A2	PLA2G2D SPLASH	view

Displaying 1 entry
GlyCosmos Lectin	UniProt ID	Lectin Name	Pathway Viewer
GL_001087	Q13018	Secretory phospholipase A2 receptor	view

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