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GRB2:SOS provides linkage to MAPK signaling for Integrins

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-354194

PubChem

R-HSA-354194

Description

Integrin signaling is linked to the MAP kinase pathway by recruiting Grb2 to the FADK1/SRC activation complex.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 11 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P02671	Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]	FGA	view
P02675	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	FGB HEL-S-78p	view
P02679	Fibrinogen gamma chain	FGG PRO2061	view
P02751	Fibronectin	FN FN1	view
P04275	von Willebrand factor	F8VWF VWF	view
P05106	Integrin beta-3	GP3A ITGB3	view
P08514	Integrin alpha-IIb	GP2B ITGA2B ITGAB	view
P12931	Proto-oncogene tyrosine-protein kinase Src	SRC SRC1	view
Q05397	Focal adhesion kinase 1	FAK FAK1 PTK2	view
Q07889	Son of sevenless homolog 1	SOS1	view

Displaying **all 3** entries
GlyCosmos Lectin	UniProt ID	Lectin Name	Pathway Viewer
GL_005388	P02671	Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]	view
GL_005389	P02675	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	view
GL_005390	P02679	Fibrinogen gamma chain	view

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