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Class C/3 (Metabotropic glutamate/pheromone receptors)

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-420499

PubChem

R-HSA-420499

Description

The class C G-protein-coupled receptors are a class of G-protein coupled receptors that include the metabotropic glutamate receptors and several additional receptors (Brauner-Osborne H et al, 2007). Family C GPCRs have a large extracellular N-terminus which binds the orthosteric (endogenous) ligand. The shape of this domain is often likened to a clam. Several allosteric ligands to these receptors have been identified and these bind within the seven transmembrane region.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 40 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O00222	Metabotropic glutamate receptor 8	GPRC1H GRM8 MGLUR8	view
O15303	Metabotropic glutamate receptor 6	GPRC1F GRM6 MGLUR6	view
O75899	Gamma-aminobutyric acid type B receptor subunit 2	GABBR2 GPR51 GPRC3B	view
P41180	Extracellular calcium-sensing receptor	CASR GPRC2A PCAR1	view
P41594	Metabotropic glutamate receptor 5	GPRC1E GRM5 MGLUR5	view
P59533	Taste receptor type 2 member 38	PTC TAS2R38	view
P59534	Taste receptor type 2 member 39	TAS2R39	view
P59535	Taste receptor type 2 member 40	GPR60 TAS2R40	view
P59536	Taste receptor type 2 member 41	TAS2R41	view
P59537	Taste receptor type 2 member 43	TAS2R43	view

Displaying 1 entry
GlyTouCan ID	KEGG GLYCAN	ChEBI	Pathway Viewer
G15021LG	G12504	4167	view

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