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Other interleukin signaling

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-449836

PubChem

R-HSA-449836

Description

Interleukins are low molecular weight proteins that bind to cell surface receptors and act in an autocrine and/or paracrine fashion. They were first identified as factors produced by leukocytes but are now known to be produced by many other cells throughout the body. They have pleiotropic effects on cells which bind them, impacting processes such as tissue growth and repair, hematopoietic homeostasis, and multiple levels of the host defense against pathogens where they are an essential part of the immune system.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 19 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P01730	T-cell surface glycoprotein CD4	CD4	view
P07333	Macrophage colony-stimulating factor 1 receptor	CSF1R FMS	view
P09603	Macrophage colony-stimulating factor 1	CSF1	view
P09919	Granulocyte colony-stimulating factor	C17orf33 CSF3 GCSF	view
P18827	Syndecan-1	SDC SDC1	view
P23458	Tyrosine-protein kinase JAK1	JAK1 JAK1A JAK1B	view
P23471	Receptor-type tyrosine-protein phosphatase zeta	HTPZP2 PTPRZ PTPRZ1 PTPRZ2 PTPZ	view
P24158	Myeloblastin	MBN PRTN3	view
P29597	Non-receptor tyrosine-protein kinase TYK2	TYK2	view
P40222	Alpha-taxilin	TXLN TXLNA	view

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