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Lactose synthesis

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-5653890

PubChem

R-HSA-5653890

Description

Synthesis of the disaccharide lactose takes place within the Golgi apparatus of epithelial cells of the lactating mammary gland. The synthesis itself is a single chemical reaction of free glucose and UDP-galactose to form lactose and UDP. For this reaction to occur, glucose is transported from the cytosol into the Golgi lumen, and B4GALT1 interacts with LALBA (alpha-lactalbumin) to modulate its substrate specificity (Brew and Hill 1975).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 3** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P00709	Alpha-lactalbumin	LALBA LYZL7	view
P11166	Solute carrier family 2, facilitated glucose transporter member 1	GLUT1 SLC2A1	view
P15291	Beta-1,4-galactosyltransferase 1	B4GALT1 GGTB2	view

Displaying **all 2** entries
GlyTouCan ID	KEGG GLYCAN	ChEBI	Pathway Viewer
G15021LG	G12504	4167	view
G74621DY	G10504 G12462	17716	view

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