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N-Glycan antennae elongation

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-975577

PubChem

R-HSA-975577

Description

N-glycans are further modified after the commitment to Complex or Hybrid N-glycans. The exact structure of the network of metabolic reactions involved is complex and not yet validated experimentally. Here we will show a generic reaction for each of the genes known to be involved in N-Glycosylation.
For a better annotation of the reactions and genes involved in the synthesis of Complex and Hybrid N-glycans we recommend the GlycoGene Database (Ito H. et al, 2010) (http://riodb.ibase.aist.go.jp/rcmg/ggdb/textsearch.jsp) for annotations of genes, and the Consortium for Functional Genomics (http://riodb.ibase.aist.go.jp/rcmg/ggdb/textsearch.jsp) for annotation of Glycan structures and reactions. Moreover, a computationally inferred prediction for the structure of this network is available through the software GlycoVis (Hossler P. et. al. 2006).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 15 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O43173	Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3	SIAT8C ST8SIA3	view
O43286	Beta-1,4-galactosyltransferase 5	B4GALT5	view
O60512	Beta-1,4-galactosyltransferase 3	B4GALT3	view
O60513	Beta-1,4-galactosyltransferase 4	B4GALT4 UNQ552/PRO1109 hCG_22565	view
O60909	Beta-1,4-galactosyltransferase 2	B4GALT2	view
P15291	Beta-1,4-galactosyltransferase 1	B4GALT1 GGTB2	view
P15907	Beta-galactoside alpha-2,6-sialyltransferase 1	SIAT1 ST6GAL1	view
P61647	Alpha-2,8-sialyltransferase 8F	SIAT8F ST8SIA6	view
Q09328	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A	GGNT5 MGAT5	view
Q11206	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4	CGS23 NANTA3 SIAT4C ST3GAL4 STZ hCG_37591	view

Displaying 1 entry
GlyTouCan ID	KEGG GLYCAN	ChEBI	Pathway Viewer
G81533KY		17012	view

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