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NFE2L2 regulating inflammation associated genes

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-9818026

PubChem

R-HSA-9818026

Description

Subpathway representing inflammatory genes regulated by NFE2L2. NFE2L2 plays a pivotal role in regulating inflammation directly (by regulating inflammation-related genes like CCL2, IL8) and indirectly (through the HO-1-NFKB axis). This role of NFE2L2 plays a role in inflammatory diseases and expands NFE2L2 role beyond the antioxidant system. (Ahmed et al, 2017; Saha et al, 2020)

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 5** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O60675	Transcription factor MafK	MAFK	view
P13500	C-C motif chemokine 2	CCL2 MCP1 SCYA2	view
Q09472	Histone acetyltransferase p300	EP300 P300	view
Q16236	Nuclear factor erythroid 2-related factor 2	NFE2L2 NRF2	view
Q92793	CREB-binding protein	CBP CREBBP	view

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