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NFE2L2 regulates pentose phosphate pathway genes

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-9818028

PubChem

R-HSA-9818028

Description

Sub-pathway for representing the pentose phosphate pathway gene regulated by NFE2L2 (NRF2). NFE2L2 directs the transcription of genes related to the Pentose Phosphate pathway which helps in programming the metabolic pathway to cope with oxidative stress and also has a significant role in cancer progression (Chartoumpekis et al, 2015; DeBlasi et al, 2020)

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 7** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O15525	Transcription factor MafG	MAFG	view
P11413	Glucose-6-phosphate 1-dehydrogenase	G6PD	view
P29401	Transketolase	TKT	view
P52209	6-phosphogluconate dehydrogenase, decarboxylating	PGD PGDH	view
Q09472	Histone acetyltransferase p300	EP300 P300	view
Q16236	Nuclear factor erythroid 2-related factor 2	NFE2L2 NRF2	view
Q92793	CREB-binding protein	CBP CREBBP	view

Displaying **all 3** entries
GlyCosmos Lectin	UniProt ID	Lectin Name	Pathway Viewer
GL_002471	P11413	Glucose-6-phosphate 1-dehydrogenase	view
GL_004020	P37837	Transaldolase	view
GL_005319	P52209	6-phosphogluconate dehydrogenase, decarboxylating	view

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