MyD88-independent TLR4 cascade

Summary
Organism
Mus musculus (house mouse)
Reactome
R-MMU-166166
PubChem
R-MMU-166166
Description
  • This event has been computationally inferred from an event that has been demonstrated in another species.

    The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

    More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P10810 Monocyte differentiation antigen CD14
  • Cd14
view
Q6PDS3 NAD(+) hydrolase SARM1
  • Kiaa0524
  • Sarm1
view
Q80UF7 TIR domain-containing adapter molecule 1
  • Ticam1
  • Trif
view
Q9JHF9 Lymphocyte antigen 96
  • Esop1
  • Ly96
  • Md2
view
Q9QUK6 Toll-like receptor 4
  • Lps
  • Tlr4
view

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026