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Gap junction degradation

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-190873

PubChem

R-MMU-190873

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 10** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O08585	Clathrin light chain A	Clta	view
P23242	Gap junction alpha-1 protein	Cxn-43 Gja1	view
P39053	Dynamin-1	Dnm Dnm1 Kiaa4093	view
P39054	Dynamin-2	Dnm2 Dyn2	view
P60710	Actin, cytoplasmic 1	Actb	view
P63260	Actin, cytoplasmic 2	Actg Actg1	view
P84091	AP-2 complex subunit mu	Ap2m1 Clapm1	view
P98078	Disabled homolog 2	Dab2 Doc2	view
Q64331	Unconventional myosin-VI	Myo6 Sv	view
Q68FD5	Clathrin heavy chain 1	Cltc	view

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