Generation of second messenger molecules
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp
| UniProt ID | Protein Name | Gene Symbol | Pathway Viewer |
|---|---|---|---|
| A8E0Y8 | Immunoglobulin superfamily member 2 |
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| O88643 | Serine/threonine-protein kinase PAK 1 |
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| P01849 | T-cell receptor alpha chain constant |
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| P01904 | H-2 class II histocompatibility antigen, E-D alpha chain |
|
view |
| P01910 | H-2 class II histocompatibility antigen, A-K alpha chain |
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| P01921 | H-2 class II histocompatibility antigen, A-D beta chain |
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view |
| P04230 | H-2 class II histocompatibility antigen, E-B beta chain |
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view |
| P04235 | T-cell surface glycoprotein CD3 delta chain |
|
view |
| P06332 | T-cell surface glycoprotein CD4 |
|
view |
| P11942 | T-cell surface glycoprotein CD3 gamma chain |
|
view |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: April 6, 2026