AKT-mediated inactivation of FOXO1A

Summary
Organism
Mus musculus (house mouse)
Reactome
R-MMU-211163
PubChem
R-MMU-211163
Description
  • This event has been computationally inferred from an event that has been demonstrated in another species.

    The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

    More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P31750 RAC-alpha serine/threonine-protein kinase
  • Akt
  • Akt1
  • Rac
view
Q60823 RAC-beta serine/threonine-protein kinase
  • Akt2
view
Q9R1E0 Forkhead box protein O1
  • Fkhr
  • Foxo1
  • Foxo1a
view
Q9WUA6 RAC-gamma serine/threonine-protein kinase
  • Akt3
view

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026