Signaling by ROBO receptors

Summary
Organism
Mus musculus (house mouse)
Reactome
R-MMU-376176
PubChem
R-MMU-376176
Description
  • This event has been computationally inferred from an event that has been demonstrated in another species.

    The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

    More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 7 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O89026 Roundabout homolog 1
  • Dutt1
  • Robo1
view
P62962 Profilin-1
  • Pfn1
view
P70658 C-X-C chemokine receptor type 4
  • Cmkar4
  • Cxcr4
  • Lestr
  • Sdf1r
view
Q03173 Protein enabled homolog
  • Enah
  • Mena
  • Ndpp1
view
Q9QZF2 Glypican-1 [Cleaved into: Secreted glypican-1]
  • Gpc1
view
Q9R1B9 Slit homolog 2 protein
  • Slit2
view
Q9WVB4 Slit homolog 3 protein
  • Slit3
view

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026