antiphospholipid syndrome

Summary
Synonym
  • APS
  • antiphospholipid antibody syndrome
Definition
An autoimmune disease that is characterized by recurrent venous or arterial thrombosis and/or fetal losses associated with characteristic elevated levels of antibodies directed against membrane anionic phospholipids (anticardiolipin).
Super Class
autoimmune disease of cardiovascular system
Disease Ontology
DOID:2988
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying all 7 entries
Gene ID Gene Symbol Description Source
350 APOH apolipoprotein H
959 CD40LG CD40 ligand
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
5327 PLAT plasminogen activator, tissue type
5624 PROC protein C, inactivator of coagulation factors Va and VIIIa

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025