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MIRAGE
cholinergic receptor nicotinic alpha 5 subunit
Summary
- Gene Symbol
-
- CHRNA5
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| signal transduction | ||
| chemical synaptic transmission | ||
| synaptic transmission, cholinergic | ||
| neuromuscular synaptic transmission | ||
| ion transmembrane transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| acetylcholine-gated channel complex | ||
| acetylcholine-gated channel complex | ||
| neuron projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| ligand-gated monoatomic ion channel activity | ||
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- acetylcholine receptor subunit
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:1324 | lung cancer | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:3907 | lung squamous cell carcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:809 | cocaine abuse | |
| DOID:9261 | nasopharynx carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1134 | FB:FBgn0266347 | ||
| 1135 | FB:FBgn0266347 | ||
| 1136 | FB:FBgn0266347 | ||
| 1137 | FB:FBgn0266347 | ||
| 1138 | Xenbase:XB-GENE-5755296 | ||
| 1140 | FB:FBgn0266347 | ||
| 1141 | FB:FBgn0266347 | ||
| 1142 | FB:FBgn0266347 | ||
| 1143 | WB:WBGene00000047 | ||
| 1144 | FB:FBgn0266347 |
