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beta-1,4-N-acetyl-galactosaminyl transferase 1

Summary

Gene Symbol

B4galnt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14421

KEGG Gene ID

mmu:14421

PubChem

14421

Alliance of Genome Resources

MGI:1342057

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Sphingolipid metabolism
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A1Z4EAV4
Q09200	(N-acetylneuraminyl)-galactosylglucosylceramide GM2/GD2 synthase GalNAc-T
Q3UN35
Q8VDF0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
ganglioside biosynthetic process	ISS
ganglioside biosynthetic process	ISO
ganglioside biosynthetic process	IMP
ganglioside biosynthetic process	IGI
ganglioside biosynthetic process	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

carbohydrate derivative biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

carbohydrate derivative metabolic process

carbohydrate derivative biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization

nutrient storage [inference]

lipid storage

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

multicellular organismal process [inference]

behavior [inference]

motor behavior

determination of adult lifespan

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

anatomical structure development [inference]

nerve development

appendage development [inference]

limb development

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Golgi membrane	ISS
Golgi membrane	ISO
Golgi membrane	IEA
Golgi apparatus	ISS
Golgi apparatus	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity	ISS
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity	ISO
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity	IMP
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity	IEA
acetylgalactosaminyltransferase activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylgalactosaminyltransferase activity

(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity

hexosyltransferase activity

acetylgalactosaminyltransferase activity

(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

beta-1,4 N-acetylgalactosaminyltransferase 2

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
acetylgalactosaminyltransferase activity
ganglioside biosynthetic process
hexosyltransferase activity
lipid glycosylation

Displaying **all 2** entries
InterPro
Glycosyltransferase 2-like
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K00725

Name

(N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase [EC:2.4.1.92]

References

7980468

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05938	2.4.1.92	G84224TW	G90562PB
R05939	2.4.1.92	G91237TK	G79389NT
R05952	2.4.1.92	G93899SO	G36476BA
R05946	2.4.1.92	G98544DH	G02657AK

Rhea

RHEA:12588

a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP + a ganglioside GM2 (d18:1(4E))

Enzyme

2.4.1.92

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP002907
Gene Name: beta-1,4-N-acetyl-galactosaminyl transferase 1

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	64828	RGD:620490
Homo sapiens	2583	HGNC:4117
Danio rerio	793635	ZFIN:ZDB-GENE-100728-3
Danio rerio	558684	ZFIN:ZDB-GENE-070112-1462
Xenopus tropicalis	100145208	Xenbase:XB-GENE-960512

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements