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MIRAGE
sonic hedgehog signaling molecule
Summary
- Gene Symbol
-
- Shh
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Autocatalytic cleavage
- Calcium
- Cell membrane
- Developmental protein
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Metal-binding
- Palmitate
- Protease
- Reference proteome
- Signal
- Transferase
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| Q63673 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| angiogenesis |
|
|
| branching involved in blood vessel morphogenesis |
|
|
| branching involved in blood vessel morphogenesis |
|
|
| vasculogenesis |
|
GO Hierarchy
- regulation of epithelial cell differentiation
- regulation of epithelial cell differentiation
biological process
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
anatomical structure morphogenesis [inference]
anatomical structure development [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
negative regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of lymphocyte proliferation [inference]
regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
regulation of hemopoiesis [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of cellular process [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
negative regulation of immune system process [inference]
negative regulation of cellular process [inference]
negative regulation of multicellular organismal process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of cell differentiation
regulation of neuron differentiation [inference]
regulation of muscle cell differentiation [inference]
regulation of cell development [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of cell adhesion [inference]
regulation of cell population proliferation
regulation of cell differentiation [inference]
positive regulation of cell differentiation
regulation of neuron differentiation [inference]
regulation of muscle cell differentiation [inference]
regulation of cell development [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of lymphocyte proliferation [inference]
regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of cell activation [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of lymphocyte proliferation [inference]
regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of multicellular organismal process [inference]
regulation of multicellular organismal development
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular region |
|
|
| obsolete extracellular space |
|
|
| endoplasmic reticulum |
|
|
| endoplasmic reticulum membrane |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| endopeptidase activity |
|
|
| patched binding |
|
|
| patched binding |
|
|
| patched binding |
|
|
| calcium ion binding |
|
GO Hierarchy
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:5844 | myocardial infarction | |
| DOID:0080855 | Parkinsonism |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 20423 | MGI:98297 | |
| 180638 | WB:WBGene00006952 | |
| 180349 | WB:WBGene00001691 | |
| 6469 | HGNC:10848 |
