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MIRAGE

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1

Summary

Gene Symbol

ST6GALNAC1

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 449516
KEGG Gene ID: ptr:449516
PubChem: 449516

Annotation

Keyword

Glycoprotein
Golgi apparatus
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A6D2XG63
H2QDY3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein glycosylation	IEA	22301074
oligosaccharide biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity [inference]

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Sialyltransferase

Functional Category

H: Coenzyme transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
sialyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29

KEGG BRITE Database

Orthology

K03479

Name

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7A) [EC:2.4.3.3]

References

10788794

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R12704	2.4.3.3	G00031MO	G28694FA
R05914	2.4.3.3 2.4.3.7	G65562ZE	G01614ZM
R05911	2.4.3.3	G57321FI	G36123IU

Rhea

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate

a β-D-galactosyl-(1→3)-[N-acetyl-α-neuraminyl-(2→6)]-N-acetyl-α-D-galactosaminyl derivative + H⁺ + CMP

Enzyme

2.4.3.3

PMID

Ortholog

Displaying entries **31 - 39** of 39 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Propithecus coquereli	105824732		PROCO09797
Equus asinus asinus	106830340		EQUAS09934
Rhinopithecus bieti	108537385		RHIBE06618
Vulpes vulpes	112920614		VULVU13462
Bos indicus x Bos taurus	113878101		BOBOX14522
Rhinolophus ferrumequinum	117013049		RHIFE07883
Balaenoptera musculus	118886799		BALMU10080
Panthera leo	122206713		PANLE04057
Ursus americanus	123803220		URSAM05532

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.3.0

Last updated: August 4, 2025