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interleukin 2 receptor subunit beta

Summary

Gene Symbol

IL2RB

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 470203
PubChem: 470203

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
H2QLL6	High affinity IL-2 receptor subunit beta p70-75
Q38J84	High affinity IL-2 receptor subunit beta p70-75
A0A6D2XAP5	High affinity IL-2 receptor subunit beta p70-75

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
immunoglobulin mediated immune response
cytokine-mediated signaling pathway	IEA	30032202
interleukin-15-mediated signaling pathway
interleukin-2-mediated signaling pathway
positive regulation of phagocytosis

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

response to stimulus [inference]

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane
external side of plasma membrane	IEA	30032202
cell surface
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytokine receptor activity	IEA	22301074 30032202
interleukin-2 receptor activity
interleukin-2 binding	IEA	30032202
interleukin-15 receptor activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

growth factor binding [inference]

interleukin-2 binding

cytokine binding [inference]

interleukin-2 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Interleukin-2 receptor subunit beta

Functional Category

C: Energy production and conversion
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cytokine-mediated signaling pathway
interleukin-2 binding

Displaying **all 5** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold
Interleukin-2 receptor subunit beta, N-terminal
Short hematopoietin receptor, family 1, conserved site

Ortholog

Displaying entries **1 - 10** of 57 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	3560	HUMAN60372
Mus musculus	16185	MOUSE16770
Rattus norvegicus	25746	RATNO37650
Canis lupus familiaris	403439	CANLF01648
Macaca mulatta	696331	MACMU00632
Monodelphis domestica	100025393	MONDO34610
Equus caballus	100069676	HORSE26308
Callithrix jacchus	100394910	CALJA20928
Pongo abelii	100460977	PONAB21883
Ailuropoda melanoleuca	100478292	AILME17494