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dolichyl-phosphate beta-D-mannosyltransferase

Summary

Gene Symbol

DPM1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

856313

KEGG Gene ID

sce:YPR183W

PubChem

856313

Alliance of Genome Resources

SGD:S000006387

Annotation

Keyword

Acetylation
Direct protein sequencing
Endoplasmic reticulum
Glycosyltransferase
Magnesium
Manganese
Metal-binding
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P14020	Dolichol-phosphate mannose synthase Dolichyl-phosphate beta-D-mannosyltransferase Mannose-P-dolichol synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
dolichol-linked oligosaccharide biosynthetic process	IMP
dolichol-linked oligosaccharide biosynthetic process	IBA
dolichol-linked oligosaccharide biosynthetic process	IEA
GPI anchor biosynthetic process	IMP
GPI anchor biosynthetic process	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

dolichol phosphate mannose biosynthetic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

glycolipid biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

carbohydrate derivative biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

glycolipid biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

dolichol phosphate mannose biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

dolichol phosphate mannose biosynthetic process

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

dolichol phosphate mannose biosynthetic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

dolichol phosphate mannose biosynthetic process

glycolipid biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

carbohydrate derivative biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via mannose

glycolipid biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IBA
endoplasmic reticulum membrane	IEA
membrane	IEA
nuclear outer membrane-endoplasmic reticulum membrane network	IDA
cell periphery	HDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

endoplasmic reticulum membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

nuclear outer membrane-endoplasmic reticulum membrane network

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

cell periphery

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
dolichyl-phosphate beta-D-mannosyltransferase activity	RCA
dolichyl-phosphate beta-D-mannosyltransferase activity	EXP
dolichyl-phosphate beta-D-mannosyltransferase activity	IDA
dolichyl-phosphate beta-D-mannosyltransferase activity	IBA
dolichyl-phosphate beta-D-mannosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

mannosyltransferase activity [inference]

dolichyl-phosphate beta-D-mannosyltransferase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dolichol-phosphate mannosyltransferase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
dolichol-linked oligosaccharide biosynthetic process
dolichyl-phosphate beta-D-mannosyltransferase activity
protein O-linked mannosylation
transferase activity

Displaying **all 3** entries
InterPro
DPM1-like
Glycosyltransferase 2-like
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K00721

Name

dolichol-phosphate mannosyltransferase [EC:2.4.1.83]

References

3053713

Alliance of Genome Resources

Expression

Displaying **all 5** entries
Location	References
mitochondrion	PMID:14576278 PMID:16823961 PMID:24769239
nuclear outer membrane-endoplasmic reticulum membrane network	PMID:10419517
cell periphery	PMID:26928762
endoplasmic reticulum	PMID:1803815 PMID:26928762
mitochondrial outer membrane	PMID:16407407

Rhea

RHEA:21184

GDP-α-D-mannose

GDP

Enzyme

2.4.1.83

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1612	breast cancer	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007360
Gene Name: dolichyl-phosphate beta-D-mannosyltransferase

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	13480	MGI:1330239
Rattus norvegicus	296394	RGD:1310120
Caenorhabditis elegans	176874	WB:WBGene00022044
Drosophila melanogaster	35240	FB:FBgn0032799
Homo sapiens	8813	HGNC:3005
Danio rerio	445202	ZFIN:ZDB-GENE-040801-115
Xenopus tropicalis	496884	Xenbase:XB-GENE-976623