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Guidelines

MIRAGE

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

Summary

Gene Symbol

Idh3b

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

94173

KEGG Gene ID

PubChem

94173

Alliance of Genome Resources

RGD:621881

Annotation

Keyword

Acetylation
Mitochondrion
Proteomics identification
Reference proteome
Transit peptide
Tricarboxylic acid cycle

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q68FX0	Isocitric dehydrogenase subunit beta NAD(+)-specific ICDH subunit beta
A6HQ80
A0A8I6AMM2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
tricarboxylic acid cycle	ISO
tricarboxylic acid cycle	IBA
tricarboxylic acid cycle	IEA
isocitrate metabolic process	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

primary metabolic process [inference]

tricarboxylic acid cycle

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

isocitrate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

isocitrate metabolic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	NAS
mitochondrion	IBA
mitochondrion	IEA
isocitrate dehydrogenase complex (NAD+)	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

tricarboxylic acid cycle heteromeric enzyme complex [inference]

isocitrate dehydrogenase complex (NAD+)

oxidoreductase complex [inference]

isocitrate dehydrogenase complex (NAD+)

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
magnesium ion binding	IEA
enzyme activator activity	ISO
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA
NAD binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity

molecular function activator activity [inference]

enzyme activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dehydrogenase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
isocitrate dehydrogenase (NAD+) activity
isocitrate metabolic process
magnesium ion binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
tricarboxylic acid cycle

Displaying **all 3** entries
InterPro
Isocitrate dehydrogenase NAD-dependent
Isocitrate/isopropylmalate dehydrogenase, conserved site
Isopropylmalate dehydrogenase-like domain

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	3420	HGNC:5385
Saccharomyces cerevisiae S288C	855691	SGD:S000004982

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026