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GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
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GALAXY
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Guidelines
MIRAGE
G00052MO
Summary
- GlyTouCan ID
-
G00052MO
- IUPAC Condensed
- Fuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-
- Motifs
- Blood group H (type 2) Leb Lewis b Ley
- Subsumption Level
- Fully-defined saccharide
- Monoisotopic Mass
- 675.26
External Links
- GlyGen
- ChEBI
- PubChem Compound
- PubChem Substance
- CarbBank
- 329 642 2537 2538 2539 3605 4591 7421 7648 7781 7847 10751 14878 15221 16398 20238 22552 22553 22554 22555 23607 25838 27637 28542 28578 28581 28594 29591 34222 34676 34848 34944 34976 34984 35241 35825 35841 36884 36921 36945 37036 37265 38055 41388 42058 42330 42425 42873 42934 43451 43710 44221 44361 44371 44543 45121 45320 45465 45861 45867 45900 45905 46554 46775 47008 47073 47183 47330 47457 48385 48510 48721 49120 49149 49439 50275 50533
3D Structures
G04690JX
G82236PZ
Organisms
| Organisms | Evidence |
|---|---|
| Oryctolagus cuniculus (rabbit) | |
| Chlorocebus aethiops (grivet) | |
| Felis catus (domestic cat) | |
| Helicobacter pylori | |
| Mus musculus (house mouse) |
Taxonomic Hierarchy
root
cellular organisms [inference]
Eukaryota (eucaryotes) [inference]
Opisthokonta [inference]
Metazoa (metazoans) [inference]
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| FUT5 | GDP-Fuc |
G61459JW
|
R |
G00052MO
|
R | |
| FUT5 | GDP-Fuc |
G61459JW
|
(CH2)8COOCH3 |
G00052MO
|
(CH2)8COOCH3 | |
| FUT3 | GDP-Fuc |
G61459JW
|
R |
G00052MO
|
R | |
| FUT3 | GDP-Fuc |
G61459JW
|
(CH2)8COOCH3 |
G00052MO
|
(CH2)8COOCH3 | |
| FUT6 | GDP-Fuc |
G61459JW
|
(CH2)8COOCH3 |
G00052MO
|
(CH2)8COOCH3 |
GlycoEpitope
- Epitope ID
- EP0018
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl 3b:a-lgal-HEX-1:5|6:d 4b:b-dgal-HEX-1:5 5b:a-lgal-HEX-1:5|6:d LIN 1:1d(2+1)2n 2:1o(3+1)3d 3:1o(4+1)4d 4:4o(2+1)5d
- WURCS
- WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5][a2112h-1b_1-5]/1-2-3-2/a3-b1_a4-c1_c2-d1
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 24533777 | The Role of Anti-LeY Antibody in the Downregulation of MAPKs/COX-2 Pathway in Gastric Cancer | Aziz F | 2014 Mar 31 |
|
| 24648450 | Structural Analysis of Determinants of Histo-Blood Group Antigen Binding Specificity in Genogroup I Noroviruses | Shanker S | 2014 Jun |
|
| 25527419 | Anti-LeY antibody enhances therapeutic efficacy of celecoxib against gastric cancer by downregulation of MAPKs/COX-2 signaling pathway: correlation with clinical study | Aziz F | 2014 Dec 20 |
|
| 25117628 | Defining the Recognition Elements of Lewis Y-Reactive Antibodies | Saha S | 2014 Aug 12 |
|
| 24692145 | Expression of CD147 and Lewis y antigen in ovarian cancer and their relationship to drug resistance | Gao J | 2014 Apr 02 |
|
| 23950139 | Recombinant Lectin-Like Domain of Thrombomodulin Suppresses Vascular Inflammation by Reducing Leukocyte Recruitment via Interacting With Lewis Y on Endothelial Cells | Lin WL | 2013 Oct |
|
| 23831595 | Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia | Ritchie DS | 2013 Nov |
|
| 24201214 | CAR T Cells for Acute Myeloid Leukemia: The LeY of the Land | Brenner MK | 2013 Nov |
|
| 23708102 | Chemoresistance Is Associated with MUC1 and Lewis y Antigen Expression in Ovarian Epithelial Cancers | Zhang D | 2013 May 24 |
|
| 23725446 | Expression of Lewis y antigen and integrin αv, β3 in ovarian cancer and their relationship with chemotherapeutic drug resistance | Gao J | 2013 Jun 01 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| A molecular basis for functional peptide mimicry of a carbohydrate antigen. |
|
J Biol Chem | 2000 May 26 | 10748116 |
| Schistosoma mansoni cercarial glycolipids are dominated by Lewis X and pseudo-Lewis Y structures. |
|
Glycobiology | 2000 Jan | 10570227 |
| Cloning and expression of beta1,4-galactosyltransferase gene from Helicobacter pylori. |
|
Glycobiology | 2000 Aug | 10929007 |
| alpha1,2Fucosyltransferase increases resistance to apoptosis of rat colon carcinoma cells. |
|
Glycobiology | 2000 Apr | 10764825 |
| Glycosylation alterations of cells in late phase apoptosis from colon carcinomas. |
|
Glycobiology | 1999 Dec | 10561459 |
