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GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
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MIRAGE
G00052MO
Summary
- GlyTouCan ID
-
G00052MO
- IUPAC Condensed
- Fuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-
- Motifs
- Blood group H (type 2) Leb Lewis b Ley
- Subsumption Level
- Fully-defined saccharide
- Monoisotopic Mass
- 675.26
External Links
- GlyGen
- ChEBI
- PubChem Compound
- PubChem Substance
- CarbBank
- 329 642 2537 2538 2539 3605 4591 7421 7648 7781 7847 10751 14878 15221 16398 20238 22552 22553 22554 22555 23607 25838 27637 28542 28578 28581 28594 29591 34222 34676 34848 34944 34976 34984 35241 35825 35841 36884 36921 36945 37036 37265 38055 41388 42058 42330 42425 42873 42934 43451 43710 44221 44361 44371 44543 45121 45320 45465 45861 45867 45900 45905 46554 46775 47008 47073 47183 47330 47457 48385 48510 48721 49120 49149 49439 50275 50533
3D Structures
G04690JX
G82236PZ
Organisms
| Organisms | Evidence |
|---|---|
| Oryctolagus cuniculus (rabbit) | |
| Chlorocebus aethiops (grivet) | |
| Felis catus (domestic cat) | |
| Helicobacter pylori | |
| Mus musculus (house mouse) |
Taxonomic Hierarchy
root
cellular organisms [inference]
Eukaryota (eucaryotes) [inference]
Opisthokonta [inference]
Metazoa (metazoans) [inference]
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| FUT5 | GDP-Fuc |
G61459JW
|
R |
G00052MO
|
R | |
| FUT5 | GDP-Fuc |
G61459JW
|
(CH2)8COOCH3 |
G00052MO
|
(CH2)8COOCH3 | |
| FUT3 | GDP-Fuc |
G61459JW
|
R |
G00052MO
|
R | |
| FUT3 | GDP-Fuc |
G61459JW
|
(CH2)8COOCH3 |
G00052MO
|
(CH2)8COOCH3 | |
| FUT6 | GDP-Fuc |
G61459JW
|
(CH2)8COOCH3 |
G00052MO
|
(CH2)8COOCH3 |
GlycoEpitope
- Epitope ID
- EP0018
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl 3b:a-lgal-HEX-1:5|6:d 4b:b-dgal-HEX-1:5 5b:a-lgal-HEX-1:5|6:d LIN 1:1d(2+1)2n 2:1o(3+1)3d 3:1o(4+1)4d 4:4o(2+1)5d
- WURCS
- WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5][a2112h-1b_1-5]/1-2-3-2/a3-b1_a4-c1_c2-d1
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 22665069 | Correlation of ADCC activity with cytokine release induced by the stably expressed, glyco-engineered humanized Lewis Y-specific monoclonal antibody MB314 | Kircheis R | 2012 Jul |
|
| 22312289 | Lewis y Regulate Cell Cycle Related Factors in Ovarian Carcinoma Cell RMG-I in Vitro via ERK and Akt Signaling Pathways | Liu D | 2012 Jan 16 |
|
| 22325774 | Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen Specificity | Feil SC | 2012 Feb 08 |
|
| 22325766 | Host Glycan Recognition by a Pore Forming Toxin | Bouyain S | 2012 Feb 08 |
|
| 22101897 | The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis Y antigen | Kuo CH | 2012 Feb 02 |
|
| 23242548 | Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x | Hotta H | 2012 Dec 15 |
|
| 22160312 | Helicobacter pylori isolates from Greek children express type 2 and type 1 Lewis and α1,6-glucan antigens in conjunction with a functional type IV secretion system | Altman E | 2012 Apr 01 |
|
| 22374728 | Expression of the carbohydrate tumour marker Sialyl Lewis A, Sialyl Lewis X, Lewis Y and Thomsen-Friedenreich antigen in normal squamous epithelium of the uterine cervix, cervical dysplasia and cervical cancer | Engelstaedter V | 2012 Apr |
|
| 23181061 | Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin | Lawrence SL | 2012 |
|
| 22550396 | Interaction ofHelicobacter pyloriwith C-Type Lectin Dendritic Cell-Specific ICAM Grabbing Nonintegrin | Miszczyk E | 2012 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| A molecular basis for functional peptide mimicry of a carbohydrate antigen. |
|
J Biol Chem | 2000 May 26 | 10748116 |
| Schistosoma mansoni cercarial glycolipids are dominated by Lewis X and pseudo-Lewis Y structures. |
|
Glycobiology | 2000 Jan | 10570227 |
| Cloning and expression of beta1,4-galactosyltransferase gene from Helicobacter pylori. |
|
Glycobiology | 2000 Aug | 10929007 |
| alpha1,2Fucosyltransferase increases resistance to apoptosis of rat colon carcinoma cells. |
|
Glycobiology | 2000 Apr | 10764825 |
| Glycosylation alterations of cells in late phase apoptosis from colon carcinomas. |
|
Glycobiology | 1999 Dec | 10561459 |
