G21856LC

Summary
GlyTouCan ID
G21856LC
IUPAC Condensed
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-
Motifs
Asialo-GM1
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
707.25
GlyGen
ChEBI
PubChem Compound
PubChem Substance
GlycoShape
Displaying 1 entry
Archetype α β
G00071MO
G11042HO
G21856LC
3D Structures
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT4 UDP-Gal
G90562PB
Cer
G21856LC
Cer
Displaying all 2 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST3GAL2 CMP-Neu5Ac
G21856LC
Cer
G03277YI
Cer
B3GALT4 UDP-Gal
G90562PB
Cer
G21856LC
Cer
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST6GALNAC2 CMP-Neu5Ac
G21856LC
ceramide
ST6GALNAC4 CMP-Neu5Ac
G21856LC
ceramide
ST3GAL6 CMP-Neu5Ac
G21856LC
ceramide
ST6GAL1 CMP-Neu5Ac
G21856LC
ceramide
ST6GALNAC1 CMP-Neu5Ac
G21856LC
Cer
KEGG BRITE Database
KEGG ID
Enzyme
References
Reactions
Displaying all 2 entries
KEGG Reaction Enzyme Acceptor Product
R05956
R05957
GlycoEpitope
Epitope ID
EP0047
Epitope Name
Asialo GM1
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:b-dgal-HEX-1:5
4s:n-acetyl
5b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(4+1)3d
3:3d(2+1)4n
4:3o(3+1)5d
WURCS
WURCS=2.0/3,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-2/a4-b1_b4-c1_c3-d1
Literature
Displaying entries 1 - 10 of 19 in total
PubMed ID Title First Author Publication Date Source
33328520 The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata Kamata K 2020 Dec 16
  • PubChem
17855742 Sulfatide binding properties of murine and human antiganglioside antibodies Townson K 2007 Aug 17
  • GlyGen
  • GlycoEpitope
12235148 Characterization of the second type of human beta-galactoside alpha 2,6-sialyltransferase (ST6Gal II), which sialylates Galbeta 1,4GlcNAc structures on oligosaccharides preferentially. Genomic analysis of human sialyltransferase genes Takashima S 2002 Nov 29
  • PubChem
11062056 Cloning, expression and gene organization of a human Neu5Ac alpha 2-3Gal beta 1-3GalNAc alpha 2,6-sialyltransferase: hST6GalNAcIV Harduin-Lepers A 2000 Nov 15
  • PubChem
10742600 Molecular cloning and functional expression of human ST6GalNAc II. Molecular expression in various human cultured cells Samyn-Petit B 2000 Apr 06
  • PubChem
10536037 Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens Ikehara Y 1999 Nov 01
  • PubChem
10206952 Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids Okajima T 1999 Apr 23
  • PubChem
9582303 A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family Amado M 1998 May 22
  • PubChem
9312075 Expression cloning of rat cDNA encoding UDP-galactose:GD2 beta1,3-galactosyltransferase that determines the expression of GD1b/GM1/GA1 Miyazaki H 1997 Oct 03
  • GlyGen
  • GlycoEpitope
  • PubChem
8920913 Molecular cloning and expression of human Gal beta 1,3GalNAc alpha 2,3-sialytransferase (hST3Gal II) Kim YJ 1996 Nov 12
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 10 in total
Title Authors Source Publication Date PubMed ID
Functional interaction analysis of GM1-related carbohydrates and Vibrio cholerae toxins using carbohydrate microarray.
  • Kim CS
  • Seo JH
  • Cha HJ
Anal Chem 2012 Aug 7 22770420
Human alpha2,3-sialyltransferase (ST3Gal II) is a stage-specific embryonic antigen-4 synthase.
  • Saito S
  • Aoki H
  • Ito A
  • Ueno S
  • Wada T
  • Mitsuzuka K
  • Satoh M
  • Arai Y
  • Miyagi T
J Biol Chem 2003 Jul 18 12716912
Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids.
  • Okajima T
  • Fukumoto S
  • Miyazaki H
  • Ishida H
  • Kiso M
  • Furukawa K
  • Urano T
  • Furukawa K
J Biol Chem 1999 Apr 23 10206952
The synthesis of 16-mercaptohexadecanyl glycosides for biosensor applications.
  • Kitov PI
  • Railton C
  • Bundle DR
Carbohydr Res 1998 Feb 9675372
Anti-GM3-lactam monoclonal antibodies of the IgG type recognize natural GM3-ganglioside lactone but not GM3-ganglioside.
  • Ding K
  • Rosén A
  • Ray AK
  • Magnusson G
Glycoconj J 1992 Dec 1305422

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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